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IMP dehydrogenase Inhibitor

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-10250A
    Triciribine phosphate sodium

    TCN-P sodium

    		 ATP Synthase Metabolic Disease
    Triciribine phosphate sodium inhibits amidophosphoribosyltransferase by an allosteric mechanism which affects the first committed step of de novo purine biosynthesis. Triciribine phosphate sodium also inhibits IMP dehydrogenase which is the first committed step of guanosine nucleotide synthesis. Tricilibine phosphate does not affect ligase activity .
    Triciribine phosphate sodium
  • HY-10250
    Triciribine phosphate

    TCN-P

    		 ATP Synthase Metabolic Disease
    Triciribine phosphate (TCN-P) inhibits amidophosphoribosyltransferase by an allosteric mechanism which affects the first committed step of de novo purine biosynthesis. Triciribine phosphate also inhibits  IMP dehydrogenase which is the first committed step of guanosine nucleotide synthesis. Tricilibine phosphate does not affect ligase activity .
    Triciribine phosphate
  • HY-114570
    Tiazofurin

    NSC 286193; Riboxamide

    		 Nucleoside Antimetabolite/Analog Orthopoxvirus Infection Cancer
    Tiazofurin (NSC 286193) is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent inhibitor of IMP dehydrogenase (IMPDH) . Tiazofurin also has anti-orthopoxvirus and anti-variola activities .
    Tiazofurin

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